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phenobarbital will minimize the extent or outcome of olanzapine/samidorphan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Robust CYP3A4 inducers lessen levels of olanzapine and samidorphan by~fifty% and ~75% respectively.phenobarbital will reduce the extent or impact of dienogest/estradiol valerate by im